For her whole life, Manu has lived as an undocumented person, first as an Argentinian immigrant in Miami and now as the “illegal” child of a human and a Septimus (a magical person). Her werewolf father wants to protect her from his people just as her human mother wants to protect Manu from hers. After the events of the first book, Manu goes on the lam with her Septimus friends, Tiago, a lobizón (a male werewolf) and Manu’s crush, Cata and Saysa, brujas (female witches) who are also secret girlfriends. They race to keep ahead of the Cazadores (basically, a cross between the cops and ICE, but with magic) who want to kill Manu for violating the laws of their portal world of Kerana.
Along the way, the teens meet non-compliant Septimus living on the fringe or hiding in plain sight who all have their own reasons for wanting to break down the walls of their oppressive society. But do they want to dismantle the system or simply reform it? The former would allow Manu to live freely and openly, while the latter would consign her to second class citizenship, with no rights and no say in her life. How much are her friends and new allies willing to risk for Manu? For the betterment of their people? All Manu wants is to finally have a home where she can be herself without fear. In Cazadora, that may be a dream beyond her grasp.